Biology Reference
In-Depth Information
FIGURE 5.5. Novel chromosome rearrangements that cause hearing loss, among
other physical findings. (A) Marker chromosome of an inverted duplication of
15q25-q26, on right, as compared with a normal chromosome 15 (left). The patient
described (Huang et al. 1998) had two normal chromosomes 15 in addition to the
marker 15. (B) Normal chromosome 2, on left, as compared with inverted chromo-
some 2 (Kozma et al. 1996). (C) Partial trisomy of 6q described by Conrad et al.
(1998) as a result of a 6;14 translocation. Arrows indicate the chromosomal break-
points. The child had two normal chromosomes 6 (on left), one normal chromosome
14 (middle) and one derivative 14, with additional 6q material attached to 14p.
