Biomedical Engineering Reference
In-Depth Information
2
Characterization
Methods for the
Determination of
Inhalation Exposure to
Airborne Nanomaterials
Christof Asbach
CONTENTS
2.1 Introduction .................................................................................................... 25
2.2 Size-Integrated and Time-Resolved Measurements ....................................... 27
2.2.1 Condensation Particle Counters .......................................................... 27
2.2.2 Diffusion Charger-Based Instruments ................................................ 29
2.3 Size-Resolved and Time-Resolved Measurements ......................................... 32
2.3.1 Instruments Based on Electrical Mobility Analysis ........................... 32
2.3.2 Instruments Based on Inertial Classification ...................................... 35
2.3.3 Instruments Based on Optical Classification ...................................... 37
2.4 Size-Resolved and Time-Integrated Measurements ....................................... 39
2.4.1 Inertial Particle Samplers ................................................................... 39
2.4.2 Thermal Particle Samplers ................................................................. 39
2.5 Size-Integrated and Time-Integrated Measurements ..................................... 40
2.5.1 Filtration Methods .............................................................................. 40
2.5.2 Electrostatic Particle Samplers ........................................................... 41
2.6 Summary ........................................................................................................ 42
References ............................................................................................................... 43
2.1 INTRODUCTION
Assessing the inhalation exposure to airborne nanomaterials requires characteriza-
tion of the workplace aerosols. These aerosols can be characterized using various
metrics, for example, the particle number, surface area, or mass concentrations.
These concentrations can be measured either as particle size-resolved distributions
or as size-integrated total concentrations. Depending on the type of measurement
or sampling device used, these data are provided as either time-resolved data or
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