A Chromatography-free Method for the Isolation of Products from Mechanochemical Reactions - Ball Milling Towards Green Synthesis: Applications, Projects, Challenges - page 201

8.4 Conclusion
The development of environmentally benign methodology is an important
aspect of the future of chemistry. When used together, ball milling and
functional resins effectively carry out organic reactions, and provide an
environmentally benign method for conducting chemical reactions and
isolating products. In essence, ball milling significantly reduces organic
solvent use during the reaction while the use of functional resins allows for
the isolation of products in a chromatography-free manner. From the work
presented in this chapter it was also demonstrated that polymer supported
reagents under mechanochemical conditions can give products and select-
ivity not observed in solution. It is expected that further studies with ball
milling and polymer supported reagents will lead to a significant advance-
ment in the both the areas of mechanochemistry and polymer chemistry.
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