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along proton-transfer pathways to or from the chromophore. Combined interpreta-
tion of structural, spectroscopic, and computational data may then converge to
resolve the big picture of the “dynamic protome” in protein matrices.
Acknowledgments VH thanks Lars Sch
afer (University of Groningen) for kindly making avail-
able Fig. 3 for this manuscript and Noam Agmon for a preprint of Shinobu et al. [ 20 ].
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