Predicting and Measuring the Sequence Distribution of Addition Polymers - Mathematical Approaches to Polymer Sequence Analysis and Related Problems - page 223

The SEC-NMR-MALDI method consists in injecting a copolymer sample in a
size-exclusion chromatography (SEC) apparatus, in collecting 60-90 fractions and
in analyzing selected fractions by NMR and by MALDI. The SEC-NMR-MALDI
method was applied to a copolymer with units of methyl methacrylate (MMA) and
butyl-acrylate (BA for brief) reacted at high conversion. Figure 10.10 reports the
bivariate distribution of chain sizes and compositions for the MMA-BA copolymer
[ 98 ]. It can be seen that the average molar fraction of MMA in the copolymer, c MMA ,

changes. At 300 kDa, c MMA D 0:30 , whereas at 200 kDa, c MMA D 0:35 .Atlower

masses c MMA increases to 0.40, 0.50 and even higher values. The results reported

in Fig. 10.10 demonstrate beyond any possible doubt that the SEC-NMR-MALDI
method is very powerful.

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